It's an issue for me in regards to new sales/new installs. My customers aren't going to like how Office 2013 looks and works- I already know it's going to be an issue. I can only sell what I can source.
But the bigger issue is going to be when I can no longer source Windows 7 OEM. That will be a major roadblock to the success of my business. That date, unless MS does a backstep on the whole Win8 thing, will be coming at the end of this year.